New PDF release: Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes

By Jae Lee,R. Scott Obach,Michael B. Fisher

serious within the removing of substances and different xenobiotics from the physique, cytochrome P450 has powerful touching on medical checks of genetic polymorphism in metabolism, attainable drug-drug interactions, and bioavailability of candidate medications. this article systematizes findings on P450 and comparable enzymes - in addition to parallel concerns shaping the pharmaceutical - to advertise the following iteration of more secure, better drugs.

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Drug Metabolizing Enzymes: Cytochrome P450 and Other Enzymes in Drug Discovery and Development by Jae Lee,R. Scott Obach,Michael B. Fisher


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