Drug Resistance in Cancer: Mechanisms and Models by James H. Goldie,Andrew J. Coldman PDF

By James H. Goldie,Andrew J. Coldman

Drug resistance in melanoma, wherein a percentage of melanoma cells evades chemotherapy, poses a profound and carrying on with problem for the powerful therapy of melanoma. the foundations underlying the organic mechanisms in the back of this phenomenon are essentially understood and defined during this quantity. despite the fact that, a deeper knowing of drug resistance calls for a quantitative appreciation of the dynamic forces that form tumour progress, together with spontaneous mutation and choice strategies. The authors search to give an explanation for and to simplify those advanced mechanisms, and to put them in a medical context. essentially defined mathematical versions are used to demonstrate the organic rules and supply an perception into tumour improvement and the effectiveness and obstacles of drug therapy. it really is compatible for people with a non-mathematical historical past and goals to augment the effectiveness of melanoma therapy.

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Drug Resistance in Cancer: Mechanisms and Models by James H. Goldie,Andrew J. Coldman

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